Salmonella Antisera
Cayman Chemical TrnscrIptIon Factr p53 96W 1ea
An inhibitor of HRV 3C protease inhibits HRV 3C protease-induced proteolysis of HRV-14 precursor polyproteins in HRV-14-infected H1HeLa cells at 2 UM inhibits replication of 49 serotypes of HRV in HRV-infected H1HeLa cells (mean EC50 0.023 UM) inhibits replication of coxsackievirus 21 coxsackievirus B3 echovirus type 11 and enterovirus 70 in virus-infected MRC-5 cells (EC50s 0.147 0.183 0.014 and 0.007 UM respectively) decreases the number of HRV-2 PFUs in and IL-8 and IL-6 secretion by HRV-2-infected BEAS-2B cells at 10 UM inhibits enterovirus 71-induced limb paralysis and decreases in survival as well as reduces intestinal lung brain stem and cardiac muscle viral loads in enterovirus-71-infected neonatal mice at 0.1 mg/kg per day
Cayman Chemical 8-Isoprostane ELISA Antiserum
An agonist of CAR (EC50 3.9 UM for the human receptor in a reporter assay)
Cayman Chemical MSH ReleaseInhIbItng Factr
A tripeptide with diverse biological activities; binds to rat striatum (Kd = 4.69 nM); decreases immobility of mice in the forced swim test (0.1 mg/kg); increases striatal concentrations of dopamine, DOPAC, 3-MT, and HVA in a mouse model of Parkinson's disease (20 mg/kg); decreases haloperidol-induced vacuous chewing in a rat model of tardive dyskinesia (2 mg/kg); reverses morphine- and enkephalin-induced analgesia in mice in a radiant heat tail-flick assay